الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Endoprosthetic reconstruction following bone tumour resection is a well-known and popular method for preserving limbs. In the early experience with limb salvage, functional outcomes were not of main interest because patients with malignant illness had extremely low survival rates.
With improvement in chemotherapy and diagnostic tools early diagnosis and management improved patients’ survival, so evaluation of function became the topic of many studies.
Correlating the functional outcome with variables like age, sex, knee component replacement and tumor pathology will allow the implementation of exclusion criteria for better refinement of functional outcomes.
This study included 20 patients who had primary bone tumor (distal femur or proximal tibia) and previously treated by wide local excision and replacement by knee tumor prosthesis with a mean age of 33.20 ± 13.76 years old.
Patients were managed at at El-Hadra University Hospital for Orthopaedic surgery and traumatology, Alexandria, Egypt, and Borg El Arab University Hospital, 14 and 6 patients respectively.
11 of the cases were males and 9 female patients, All patients had primary bone tumor either distal femur or proximal tibia, 17 patients had osteosarcoma (85%), 2 patients had chondrosarcoma (10%) and 1 patient had Giant cell tumor (5%).
12 patients had Distal femur lesion (60%) and 8 patients had proximal tibia lesion(40%).
Functional assessment used to evaluate patients based on the Musculoskeletal Tumor Society functional evaluation system.
The average score of 4 visits was calculated and signed as the functional score.
The mean functional score for all patients was 68.71%, the maximum functional score was 81.67% while the minimum was 55.0%.
Many factors correlated to mean functional score, younger patients with distal femur lesions showed better functional score, also patients with early management and early post operative mobilization showed better results.
One patient 5% showed local recurrence which needed amputation later on.
In this study one case with proximal tibia tumor prosthesis showed infection, one of them was superficial skin infection which managed by debridement and implant retaining but the other managed by implant removal and spacer after recurrence of infection after two sessions of debridement at the end of the period of the study with overall 10% infection rate.
The prosthesis survival in this study was 90%, 2 cases of failure (10%) one of them done spacer due to infection and the other was due to local recurrence and done amputation.
In this study one patient died, the cause of death was lung metastasis