الفهرس 
Epidemiology and PathophysiologyOnly 14 pages are availabe for public view
 |  | from | 138 |  |  |
| | | from | 138 | | |
Abstract
Cirrhosis is a gradually developing chronic disease of the liver which always involves the organ as a whole. It is the irreversible consequence and final stage of various CLDs of different etiology or the result of long-term exposure to various factors. The extent of the morphological changes depends on the cause and stage of cirrhosis.
Accordingly, there is a wide spectrum of morphological findings and clinical symptoms. The variations of this disease range from symptomfree conditions, non- characteristic complaints, and different laboratory findings through to life-threatening complications (Parke et al., 2015). Polypeptide human prolactin hormone is synthesized and secreted
from the lactotrophic cells of the anterior pituitary gland. The human
PRL molecule is arranged in a single chain of 199 amino acids with three
intramolecular disulfide bonds (Freeman et al., 2000).