الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Smoking is widely regarded as the strongest modifiable risk factor for periodontal disease progression and has been associated with increased risk of periodontal attachment loss and poorer clinical outcome of non-surgical or surgical periodontal therapy, so adjunctive therapies may prove to be more effective than conventional treatment only. Ozone is a powerful oxidizing agent with a potent antimicrobial effect. It has also immunostimulating, anti-hypoxic and biosynthetic effects. This study evaluates the effect of the subgingival application of ozonated olive oil gel as an adjunct to scaling and root planning (SRP) in smokers with periodontitis. A split-mouth randomized clinical study was conducted in 30 patients (15 smokers and 15 non-smokers) receiving scaling and root planning alone in randomly selected quadrants and scaling and root planning with the subgingival application of ozonated olive oil gel in the other quadrants. Periodontal clinical parameters and plaque sample were performed at baseline and after 6 weeks for all patients. Plaque samples were cultured anaerobically for detection of p.gingivalis and A.actinomycetemcomitans. Bacterial count showed a higher significant reduction in scaling and root planning combined with ozonated olive oil gel compared to the results of scaling and root planning alone. There was more favorable outcome in all clinical parameters in scaling and root planning combined with ozonated olive oil gel compared to SRP only, but the difference was statistically non-significant.