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العنوان
Value of CHA2DS2-VASC Score as Predictor of Contrast-Induced Nephropathy in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention /
المؤلف
Khalil, Dalia Sobhy.
هيئة الاعداد
باحث / داليا صبحي خليل
مشرف / مدحت محمد عشماوي
مشرف / سامح سمير خليل
مشرف / محمد احمد البربري
الموضوع
Cardiovascular Medicine.
تاريخ النشر
2023.
عدد الصفحات
132 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
27/8/2023
مكان الإجازة
جامعة طنطا - كلية الطب - امراض القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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Abstract

PCI reduces ischemic complications in NSTEMI patients. CIN can cause renal dysfunction, longer hospital stays, and death in PCI patients. In susceptible patients, intravascular administration of radio-opaque contrast media causes CI-AKI. Hypovolemia, contrast, and eGFR cause CIN. CHA2DS2-VASc predicts non-rheumatic AF stroke risk (AF). Congestive heart failure, hypertension, older age, diabetes, stroke or TIA, and female gender are CHA2DS2-VASC risk factors for coronary artery disease. Previous studies have shown the relationship between CHA2DS2-VASc scores and coronary artery disease and acute myocardial infarction and can predict in hospital and long-term adverse clinical outcomes, including mortality in stable CAD, acute coronary syndrome, and CHA2DS2-VASC score of >2 was an independent predictor of acute stent thrombosis, regardless of AF. CHA2DS2-VASC threatens CIN. CHADS2 predicts CIN risk in stable CAD patients undergoing elective PCI. This study examined CHA2DS2-VASC for CIN in NSTEMI patients undergoing PCI. 200 non-STMI patients underwent PCI. Tanta’s cardiology unit conducted the study. In the present study: 49 of the 200 patients had CIN with a percentage of 24.5%. 22.4% of the patients with CHA2DS VASC score ≤1 had CIN and 77.6% of the patients with CHA2DS VASC score ≥ 2 had CIN with a statistically significant difference. The mean age of the patients was 58.39 years, and the median was 59 years old. 56.5% of them were males. 52.5% of the patients had HTN, 38.5% had DM, 32% had anemia and 6.5% had CHF. The mean pre-intervention creatinine level of the patients was 0.94 and the median was 0.99. The mean post-intervention creatinine level was 1.07 and the median was 1. there was a statistically significant difference between the pre- and post- intervention creatinine levels in the studied sample. 45% of the patients had a CHA2DS VASC score ≤ 1 and 55% of them had CHA2DS VASC score ≥ 2. There were non-significant differences between the patients with or without CIN as regards the age and RBS. There were statistically significant differences between the two groups regarding the sex, HTN, DM, anemia, CHF, HGB, pre- and post-intervention creatinine level. 95% of the patients with CIN had resolution while 4.1% of them went into dialysis. there were significant positive correlations between the presence of CIN and female gender, HTN, DM, anemia, CHF, pre- and post-intervention creatinine level and CHA2DS VASC score. There was also a significant negative correlation between the presence of CIN and HGB. CHA2DS2- VASc score had sensitivity (77.6%) and specificity (52.3%) as a predictor for post-PCI CIN.