الفهرس 
RHEUMATOID ARTHRITISOnly 14 pages are availabe for public view
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Abstract
ABSTRACT
Background: End-stage renal disease (ESRD) is the advanced stage of a progressive loss of kidney function. About 10% of all patients with lupus nephritis (LN) eventually progress to ESRD, which may necessitate renal replacement therapy (RRT), such as haemodialysis (HD). Assessment of lupus activity after haemodialysis initiation is crucial in improving outcomes. This issue is still under consideration by researchers.
Aim of the Work: The goal of this study is to analyze lupus activity in LN patients with ESRD treated with hemodialysis
Patients and Methods: 70 LN patients were divided into two groups: group A (35 patients) who were ESRD treated with haemodialysis, while group B (35 patients) who were chronic kidney disease (CKD) stage 3, 4. Non-renal systemic lupus erythematosus disease activity index (nrSLEDAI) score was used to assess lupus activity in both groups.
Results: group A (haemodialysis group) exhibited considerably declined lupus activity compared to group B (CKD) group. With long term period maintenance on haemodialysis, there was an obvious remission in both clinical and serological parameters of lupus activity. Current doses of oral corticosteroids were less in group A than group B.
Conclusion: The current study’s findings suggest that haemodialysis improves lupus activity clinically and serologically in what has been called burn-out phenomenon.