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Abstract
This study is a prospective observational study aiming at detecting the risk factors, the most common causative organisms and the treatment outcome of chemotherapy-induced febrile neutropenic episodes among cancer patients. It included cancer patients presenting to Kasr Alainy center of clinical oncology and nuclear medicine ( NEMROCK ) with chemotherapy-induced neutropenic fever. Analysis of different factors affecting mortality and total duration till defeverescence was done. The study was conducted during the period from May 2014 to October 2014. A total of 70 patients were studied, 38 males and 32 females, with a median age of 45 years. Most common diagnosis was acute myeloid leukemia (51.4%) with the majority of patients developing febrile neutropenia during the induction phase of treatment. Fever, cough, dyspnea,tenderness at site of central venous catheters and diarrhea were the predominant symptoms. Primary site of infection was not found in 70% of patients while the remaining patients had pulmonary, gastro-intestinal , central venous catheter infection and skin/soft-tissue infection