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Abstract
Background and Objectives: Wharton{u2019}s jelly (WJ) is considered an easily accessible source of Mesenchymal stem cells (MSC) , that doesn{u2019}t require special invasive procedures . MSC are multipotent cells that can differentiate to almost all layers of the body (ectoderm , mesoderm , endoderm ) . Endothelial progenitor cells are (EPCs) primitive cells that have a crucial role in angiogenesis and revascularization . with increasing promise in manufacturing of natural vascular substitutes invitro The aim of the work is studying the endothelial differentiation of WJ derived cells under different culture conditions (WJ-MSC , WJ explants , and after enzyme digestion