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Abstract
To evaluate the usefulness of magnetic resonance spectroscopy (MRS) in differentiating bilirubin encephalopathy from severe hyperbilirubinemia in neonates. The study was conducted in the neonatal intensive care unit (NICU) at children`s hospital of Cairo university in the period between October 2013 to June 2014.The study included thirty neonates presenting with peak TSB greater than 20mg/dl. Eighteen cases presented with severe hyperbilirubinemia and classified as neonatal hyperbilirubinemia group (NH group) while twelve cases presented with signs of bilirubin encephalopathy and classified as neonatal bilirubin encephalopathy group (NBE group). All patients underwent MRS and conventional magnetic resonance sequences. The spectroscopic region of interest was the basal ganglia and a special resolution of 1.0 cm{u289B} was obtained