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العنوان
Enaminones as building blocks for synthesis of poly-functionalized bioactive heterocyclic ring systems /
الناشر
Mohamed Ramadan Abdelaziz ,
المؤلف
Mohamed Ramadan Abdelaziz
هيئة الاعداد
باحث / Mohamed Ramadan Abdel-Aziz
مشرف / Magda Ahmad Abdallah
مشرف / Thoraya A. Farghaly
باحث / Mohamed Ramadan Abdel-Aziz
تاريخ النشر
2014
عدد الصفحات
165 P. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Organic Chemistry
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 191

Abstract

The original work of the submitted thesis consists of four research projects: In the first project: New series of 1,3,4-thiadiazoles have been prepared via reaction of 1,3,4-thiadiazolenaminones with N-phenyl 2-oxopropanehydrazonoyl chloride in dioxane in the presence of triethylamine. Also, some new heterocycles incorporating 1,3,4-thiadiazole ring were obtained by reaction of 1,3,4-thiadiazolenaminones with nitrogen nucleophiles like hydrazine hydrate, 3-amino-1,2,4-triazole and 2-amino- benzimidazole. Moreover, the relation between the structure of the products and their activity towards some microorganisms was studied