الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The metastasis is the spread of cancer from one part of the body to another. Two-thirds of patients with cancer will develop bone metastases. Breast, prostate and lung cancer are responsible for more than 80% of cases of metastatic bone disease. The spine is the most common site of bone metastasis. A spinal metastasis may cause pain, instability and neurological injuries.
Patients with spinal mechanical instability typically require surgical stabilization. Since radiation or systemic treatment do not treat spinal instability, an unstable spine should be surgically stabilized to allow pain palliation and to prevent neurologic compromise & spinal deformity progression, Increasing SINS (the Spinal Instability Neoplastic Score) correlates with increasing severity of pain and functional disability.
Surgical treatment of spinal metastases maintains a reasonable quality of life by preserving patients’ normal neurological and ambulatory function as well as controlling pain.
Surgery is often one component of a multimodal approach to spinal metastases, often coupled with chemotherapy and radiation.
Determination of the appropriateness of invasive management such as multi-level decompression and stabilization requires accurate pre-operative estimation of survival.
When treating patients with vertebral metastases, surgical strategy is mainly based on life expectancy, primary site of tumor, and staging. This helps determine which patients will benefit from surgery and the type of procedure.
The main aim of this study was to analyze the outcomes of surgical treatment of patients with spinal metastases in spine unit in Assiut University Hospital regarding the pain control, neurological status and ambulatory status as well as survival rate.
This prospective case series study was conducted in Orthopaedic department Spine Unit, Assiut University hospitals in the duration from 10/2019 to 9/2021. This study was conducted on 30 patients with spinal metastases who underwent surgical treatment.