الفهرس 
GESTATIONAL DIABETESOnly 14 pages are availabe for public view
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Abstract
Background: The term intermittent fasting, when used for health reasons or weight loss, has been used to describe various types of caloric restriction. Insulin resistance has long been known to improve with fasting.
Objective: Assessment of the impact of intermittent fasting on incidence of gestational DM in overweight pregnant women in 3rd trimester and its effect on maternal and neonatal outcomes.
Methods: A total of 278 obese pregnant women were divided into two groups; group A included women who fast 16 consecutive hours per day including sleeping hours with all energy intake during the other 8 hours window of the day. group B included women who fast with the same life style. The study was conducted for 12 weeks. Maternal weight assessment was done just before delivery. Mode of delivery was reported. Screening of DM was done. Fetal assessment was done using Apgar score 1 and 5 mins and fetal weight at the time of the labor.
Results: Intermittent fasting was associated with increased risk of occurrence of prediabetes which was marginally statistically significant. However, effect on occurrence of GDM or the composite incidence of prediabetes and GDM was not statistically significant. Also, after adjustment for age and baseline BMI, there was no statistically significant effect of intermittent fasting and composite occurrence of GDM or prediabetes.
Conclusion: Intermittent fasting in the 3rd trimester of pregnancy has no impact neither on the incidence of gestational DM in obese pregnant women nor maternal and neonatal outcomes.