الفهرس 
Tile : Role of Apparent Diffusion Coefficient in Assessment of Loco-regional Nodal Spread in Cancer Rectum: Correlative study with Histo-pathological findings
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Abstract
Neoadjuvant treatment with chemoradiotherapy followed by total mesorectal excision in rectal cancer has led to a remarkable reduction in local relapse rates (Fornell-Perez et al, 2020).
Hence this combination has become the standard treatment for patients with locally advanced rectal cancer; accurate identification of lymph node involvement has become crucial for prognostic and therapeutic decision making (Ge Yu-xi et al, 2020).
Characterizing the involvement of lymph nodes is a very important prognostic marker in rectal cancer patients as it determines the local recurrence and overall survival rates. To date, the gold standard for lymph node characterization is histology of the surgical specimen. However, preoperative characterization is beneficial because neoadjuvant chemo-radiation has been shown to decrease the incidence of local relapse in high risk patients, such as those with lymph node involvement (Ianuş et al, 2020).
Magnetic resonance imaging (MRI) is currently used widely for
assessments of lymph node. While the size and morphology of
lymph nodes determined on conventional MR images are often
used to evaluate the extent of malignant disease, this imaging
modality does not have a satisfactory sensitivity or specificity for these evaluations because malignant disease may be present
even in very small nodes