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العنوان
Studies with functionally substituted heterocycles: synthesis of some new heterocycles containing nitrogen and/or sulfur /
المؤلف
Mahmoud Hassan Mohamed Allam,
هيئة الاعداد
باحث / Mahmoud Hassan Mohamed Allam
مشرف / Said Ahmed Soliman Ghozlan
مشرف / Ismail Abdelshafy Abdelhamid
مشرف / Amr Mohammed Abdelmoniem
الموضوع
Organic Chemistry
تاريخ النشر
2022.
عدد الصفحات
69 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Biochemistry
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 131

Abstract

Abstract: The thesis is composed of an introduction and two original parts. In the first part, “N-carbamimidoyl4-((3-oxocyclohex-1-en-1-yl)amino)benzenesulfonamide” and “N-(4-(N-carbamimidoylsulfamoyl)phenyl)-2-
cyanoacetamide” were used as precursors for the synthesis of a novel series of the respective 4-(2-amino-3-
cyano-4-aryl-tetrahydroquinolin-1-yl)-N-carbamimidoylbenzenesulfonamide and 4-(6-amino-3,5-dicyano-2-
oxo-4-arylpyridin-1-yl)-N-carbamimidoylbenzenesulfonamide derivatives. “In the second part, synthesis of
some novel 9,10-diaryl-octahydroacridine-1,8-diones incorporating sulfamethoxazole was achieved through the
reaction of cyclic enamine with incorporated sulfamethoxazole moiety with dimedone and aromatic aldehydes.”
The work is extended to synthesize some heteroaryl substituted octahydroacridine-1,8-diones. The chemical
constitution of all newly synthesized compounds are unambiguously verified based upon the different spectral
tools and elemental analysis.