الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Preeclampsia is a multifocal syndrome characterized by hypertension and organ system involvement. It is associated with serious complications such as hemorrhage, pulmonary edema, cerebrovascular accidents and coagulopathy. The risk for these complications is 10 to 30 folds higher among parturients with severe preeclampsia and eclampsia.Judicious fluid resuscitation is essential in women with preeclampsia management. Hypovolemia exacerbates acute kidney injury, while volume overload results in pulmonary edema.The IVC is a highly compliant vessel that changes its diameter in response to variations in blood pressure and volume changes.Cardiovascular complications are quite common and contribute to poor prognosis in these patients.This study evaluated the correlation between ultrasonographic measurement of IVC diameter and collapsibility index with arterial blood pressure in sever preeclampsia and eclampsia.This prospective observational study was conducted at the intensive care unit (ICU) of Mansoura University Hospital from September 2021 to August 2022. Eighty four postpartum females aged between 18 and 45 years old were enrolled for participating in this study according to severity of preeclampsia as defined by the guidelines of the American College of Obstetricians and Gynecologists (ACOG).Patients were managed according to our institution protocol. Demographic data of the patients were recorded. Blood pressure measurement along IVC diameters and collapsibility index were measured at time of admission to ICU and every 6 hours for 24 hours.The maximum and minimum IVC diameters assessed using the subcostal long-axis view and the collapsibility index was calculated using the formula: IVC-CI = (maximum IVC diameter– minimum IVC diameter)/maximum IVC diameter, expressed as percentage.Results: There was significant increase of IVC diameter on inspiration and expiration at 6,12,18 and 24 hour when compared with their value at admission along with decrease Arterial blood pressure and correction of hypovolemiaWhile there was significant decrease of IVC collapsibility index at 6,12,18 and 24 hour when compared with its value at admission along with decrease Arterial blood pressure and correction of hypovolemia.There was significant moderate negative correlation between SBP and each of IVC diameter on inspiration , IVC diameter on expiration. P < 0.001 for each. r= -0.62,r= -0.588 respectively. There was significant moderate positive correlation between SBP and collapsibility index P<0.001 .r= 0.526There was significant moderate negative correlation between DBP and each of IVC diameter on inspiration and ivc diameter on expiration P<0.001 for each.r= -0.539r= -0.495 respectively. Significant moderate positive correlation was found between DBP and collapsibility index P<0.001 . r= 0.49. There was significant moderate negative correlation between MAP and each of IVC diameter on inspiration , IVC diameter on expiration . P<0.001 for each . r= -0.62r= -0.538respectively.