الفهرس 
Comparative study between the efficacy of long-pulsed Neodymium- YAG laser and Fractional CO2 laser in the treatment of striaedistensae
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Abstract
Stretch marks, or StriaeDistensae (SD) are the lesions of the
dermis caused by its linear atrophy at the sites of stretching. They occur in
more than 70% of pregnant women and adolescents as a result of cutaneous
stretching. This study aimed at evaluating and comparing the clinical and
histological efficacy of the fractional CO2 laser versus the Long Pulsed (LP)
Nd: YAG laser in the treatment of Striae Alba. Patients/Methods: Thirty
female subjects having bilateral symmetrical stretch marks were managed by
the LP Nd: YAG laser on the right side and the fractional CO2 laser on the
left side. The laser treatment course consisted of 3 sessions with an interval
of 3 weeks. The patient satisfaction score and the Global Aesthetic
Improvement Scale (GAIS) were employed in the study in order to assess the
improvement 3 months after therapy. Punch biopsies measuring 4 mm were
extracted from one lesion on each side at baseline and after the last treatment
session by 3 months to evaluate the thickness of both collagen and
epidermis.
Results:Clinical improvement was more significant in the lesions treated by
the LP Nd:YAG laser than those treated with the fractional CO2 laser. The
patient satisfaction score and the GAIS were higher with a statistically
significant value in the side treated by the LP Nd:YAG laser. Collagen and
epidermal thickness increased more in the LP Nd: YAG laser treated lesions
in comparison to their thickness in the fractional CO2 laser managed lesions,
but this difference did not have a statistical significance.
Conclusion:Theclinical efficacyof the LP Nd-YAG laser exceeded that of
the fractional CO2 laser in the treatment of striae Alba without severe side
effects in spite of the insignificant histological difference between the two
lasers.