الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
PCOS is a common endocrinal condition in females of reproductive stage, and it is now believed a complicated multigenic condition in terms of etiology. Insulin resistance and compensatory hyperinsulinism cause androgen excess in polycystic ovarian syndrome.
Females with PCOS and PCOM are at increased danger of hyper-response and ovarian hyperstimulation syndrome (OHSS), so we consider acts throughout stimulation to prevent OHSS like segmental IVF, coasting, change of trigger.
Elective embryos freeze all strategy next to using GnRH antagonist protocols and GnRH agonist triggering is becoming a progressively significant portion of ART to decline the risk of OHSS in PCOS cases.
We designed a retrospective study on 227 females diagnosed with infertility due to PCOS. COS with GnRH antagonist regimen and triggered by GnRH agonist divided into two groups; the first group triggered by 0.1 mg and the second group with 0.2mg of Decapeptyl. The two groups after that underwent ICSI and frozen-all policy followed by vitrified warmed embryos transferring in an artificial endometrial preparing cycle in the 3 years between April 2018 to December 2020. We assessed the number of oocytes retrieved, the number of MII oocytes, the fertilization rate, the number of class A embryos (Day 3 and Day 5), the number of vitrified embryos and the pregnancy rate in two groups for Day 3 and Day 5 embryos.
According to our results, the number of oocytes retrieved and the MII oocytes were higher in group B. while the fertilization rate is higher in group A. the number of Day 3 class A embryos was higher in group B while the difference in Day 5 embryos was not statistically significant between the two groups. However, the number of Day 3 vitrified embryos in group B was better, and the difference in Day 5 embryos was not statistically significant. The difference in the pregnancy rate of Day 3 thawed embryos was not statistically significant, while the rate in Day 5 thawed embryos was higher in group A.
So we recommend using triptorelin 0.1 mg for triggering final oocyte maturation if the embryos will be planned to be cryopreserved on Day 3 or 5 to obtain the best result and cost saving.