الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Traumatic brain injury (TBI) is one of the leading causes of death and disability in Egypt and worldwide and accounts for a significant proportion of emergency visits and hospitalizations.
Accurate assessment of TBI is required in various medico-legal cases such as medical malpractice and compensation claims. Biomarkers have been recently used for evaluation of TBI severity and prediction of intracranial CT lesions and neurological outcomes.
The present study aimed to evaluate the diagnostic and prognostic abilities of serum ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and total Tau (T-Tau) in patients with mild to moderate TBI.
The study involved 85 patients with mild to moderate TBI and 85 control participants. Data was collected in a specially designed sheet (Appendix I) including; demographic data, data related to the injury, clinical manifestations, head CT findings, serum levels of UCH-L1 and T-Tau, treatment, and 3-month outcome.
The study revealed the following results:
I. Demographic data:
The age of TBI patients ranged from 18 up to 72 years with a mean of 35.80 ± 14.67 years. Most of the patients were in the age group (18-29 years). Male patients outnumbered female ones in all age groups with male to female ratio of 4.67:1.
The majority of patients (83.5%) were from urban areas while 16.5% belonged to rural ones.
The highest percentage of the studied TBI patients were manual workers (36.5%) followed by unemployed individuals (17.6%) then employees, students, and housewives (15.3% each).