الفهرس 
Immune thrombocytopeniaOnly 14 pages are availabe for public view
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Abstract
Immune thrombocytopenia (ITP) is a common bleeding disorder of childhood that characterized by isolated thrombocytopenia (platelet count <100,000 /micro Liter with normal white blood cell count and hemoglobin level) in the absence of other disorders, causing thrombocytopenia.
Helicobacter pylori (H. pylori) is a common organism that is present in about 50% of the global population. Besides to gastrointestinal diseases, there is evidence suggests H. pylori involvement in ITP.
This cross sectional study was conducted on ninety five patients who were recruited from Hematology Unit, Pediatric Department, Menoufia University Hospitals. The study was held in the period from June 2021 to June 2022; to detect the association between Helicobacter Pylori (H. Pylori) infection and immune thrombocytopenia in children (ITP).
Inclusion criteria:
Based on the criteria of the American Society of Hematology (ASH), children were diagnosed with ITP when the initial platelet count is < 100x103/µL, with normal Hb% and total leukocytes count (TLC).
Exclusion criteria:
Children with other causes of thrombocytopenia such as; HCV, HBV, or HIV, drugs, lymphoproliferative disorders, other auto-immune disorders, and children with active life-threating bleeding at the time of recruitment were excluded .
All studied patients were subjected to the followings:
IV. Full history taking:
1. Personal history (name, age at time of presentation, sex).
2. History of present illness (bleeding according to (site- grade- onsetcourse- duration - association with fever, arthralgia, arthritis, weight loss and bone ache).
3. History of (previous bleeding- previous surgery- febrile illness- contact to COVID-19 patient)
4. Drug history.
5. History of transfusion of blood products.
6. Family history of hematological disease.
7. Modality of treatment among children with ITP.
V. Thorough clinical examination with emphasis on:-
General condition
Bleeding signs and grade of bleeding .
Skin examination (purpura, ecchymosis), color (pallor, jaundice and cyanosis).
Lymph node examination (site, size, shape, and consistency).
Abdominal examination (hepatosplenomegaly and masses).