الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Type 2 diabetes (T2D) in elderly patients is associated with accelerated loss of skeletal muscle mass and strength . Patients with T2D are predisposed to more severe physical disability, which could be associated with a significant reduction in lean body mass and quality. Vitamin D deficiency influences bone metabolism. Moreover, studies have demonstrated that vitamin D deficiency plays key role in the pathophysiology of risk factors of metabolic syndrome which increase insulin resistance and obesity. Aim of work: examine the association between muscle function, and body composition, vitamin D status, and blood glucose in elderly women with type 2 diabetes (T2D) and metabolic syndrome. Subjects and methods: Fivty post-menopausal women + 65 years with a diagnosis of T2D and metabolic syndrome (METS). All patients will be subjected to Comprehensive Geriatric Assessment, Anthropometry and body composition: Body height and weight, waist and hip circumferences, body mass index (BMI), muscle mass (MM), and visceral fat mass (VFM) and Physical performance tests: Handgrip strength, The Timed up and Go (TUG), The arm curl test, The 30-s Chair Stand test. Laboratory assessment of vitamin D (25-hydroxyvitamin D [25-OH D]) level in the serum, Total Lipid Profile (LDL, HDL, Cholesterol and Triglycerides) and Fasting blood glucose. Results: Vitamin D deficiency was found to be highly prevalent in the examined group of elderly patients. The study revealed a correlation between vitamin D deficiency and only the arm curl test. |