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العنوان
Study the expression of DYRK1B Gene and Its Association
with Metabolic Syndrome Among The Egyptians /
المؤلف
Yara Ahmed Mohamed Mohamed Ali,
هيئة الاعداد
باحث / Yara Ahmed Mohamed Mohamed Ali
مشرف / Hamdi Mahmoud Hassaneen
مشرف / Mohamed Ali El-Desouky
مشرف / Khalda Sayed Amr
مشرف / Gehan Safwat Mohamed
الموضوع
Biochemistry
تاريخ النشر
2022.
عدد الصفحات
73 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Chemistry (miscellaneous)
تاريخ الإجازة
5/6/2022
مكان الإجازة
جامعة القاهرة - كلية العلوم - Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 118

from 118

Abstract

disease is employed to explain the metabolic syndrome (MetS).
Likewise, genetic differences related to metabolic syndrome play a key role in its
prevalence and side effects. This study aims to explore the expression of DYRK1B
and its association with metabolic syndrome in a small cohort of Egyptian.
Materials and methods: A total of 100 adult Egyptians (50 with MetS and 50
healthy control subjects) were incorporated to this study. Clinical, biochemical and
anthropometric analysis were evaluated. Relative gene expressions of DYRK1B
were compared between two groups of subjects using quantitative real time PCR.
Results: The results showed substantial overexpression in DYRK1B (p<0.05) in
MetS subjects when compared with the healthy control subjects.
Conclusion: This is the first study to impart evidence that DYRK1B is highly
expressed among the MetS subjects.