الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
It is well known that some degree of endothelial cell loss will be present at any cataract surgery. Protection of corneal endothelium during cataract surgery is critical for achieving good visual outcomes. Maintenance of corneal clarity relies heavily upon the functionality of healthy endothelial cells and an intact pumping system designed to remove fluid from the corneal stoma. The aim of this study was to assess corneal endothelial changes by using specular microscopy, after intracameral injection of ceftazidime in uncomplicated phacoemulsification. Ceftazidime, a third-generation cephalosporin was used in Sweden following an epidemic caused by a Gram-negative bacterium. The preparations used in this study were reconstituted from 250 mg vial of ceftazidime (fortum). Commercial preparations of cephalosporins for intracameral use had not been available. Previously, it has also been reported that betadine instillation in the conjunctival sac, few minutes before surgery decreases the incidence of occurrence of endophthalmitis. However, it has been shown that when the two methods are combined (Betadine and intracameral antibiotics), there is an additive effect in further decreasing the microbial load which leads to endophthalmitis.