الفهرس 
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Abstract
Due to its high level of tannin and ellagic acid, pomegranate peel is more efficient than juice when it comes to preventing the growth of P. gingivalis and A. actinomycetemcomitans biofilm.
Pomegranate genotype impacts antibacterial effect owing to variable tannin and ellagic acid volumes, we can presume. However, the method of extraction utilised (alcohol or water) had a significant impact on antibacterial content of pomegranate peels, as alcohol extract was more strong than aqueous extract in terms of the amount of antibacterial content.
Aqueous peel extract was favoured over alcoholic peel extract since it was less expensive to produce and required less time in the soxhelt apparatus. However, the results indicated just a little difference between the two extracts.
The purpose of the study was to evaluate the clinical efficacy of pomegranate extract on Porphyromonas gingivalis and A.A bacteria and their influence on the pH of the patient’s saliva.
Methodology:
In vitro: optical density and disc diffusion techniques were used to detect bacterial growth and compare the effects of pomegranate and CHX.
To see how the pomegranate and CHx mouthwash affected salivary pH, plaque index, and bleeding index, a double-blind randomised clinical experiment including 45 children was conducted.
Results
OD.118 (.02) for P.gingivalis and.015 (.01) for AA were observed after 1 hour of incubation followed by aqueous extract and 100 percent pomegranate juice, respectively, in vitro.
After 24 hours of incubation, chlorhexidine demonstrated a more durable antibacterial effect than pomegranate juice 100%, whose antibacterial efficacy progressively decreased after 24 hours of incubation.
Second, compared to patients who used chlorohexdine, the pomegranate extract group had a higher saliva PH mean 6.91 ( 0.29), which was deemed gold slandered, than those who used chlorohexdine.
Using pomegranate for at least seven days significantly reduced the plaque index and bleeding index in patients.
Rather of seeing pomegranate peel as a waste product, we may see its immense potential as a pioneering antibacterial and anti-inflammatory mouthrinse that can take the place of chemical mouthwashes that are harmful to children’s mouths.