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Abstract Foundation; Central sensory system (CNS) oddities are the most genuine inherent irregularities. Ultrasound assessment is a powerful and noninvasive methodology for pre-birth determination of these peculiarities, Aim and targets; to Detecte the extent of C.N.S deformities in patiens going to fetomaternal unit at Minia college and break down the connected elements at second trimester ”22-28 weeks ”, and to detecte the indicative precision of Ultrasound in conclusion of CNS mutations, Subjects and techniques; This is planned review, was directed on 100 ladies who alluded to Fetomaternal Unit at Minia University for any C.N.S irregularities, in the period among September2019 and September 2020, Result; 35% cases had family background of innate fetal distortions and 8 % cases had family background of C.N.S fetal contortions. 42% cases had history of aneuploidy and 46% cases had history of intrinsic diseases, end; layered ultrasonography assumes a significant part in recognition and determination of some fetal focal sensory system inconsistencies. In any case, a few irregularities might be hard to be identified by two layered ultrasonography because of position of the embryo. For instance, the procurement of the middle plane might be inconceivable with 2D transabdominal ultrasound and require unique skill in transvaginal transfontanelle filtering, however in numerous way its considered a decent temporary diagnosing device for evaluating for fetal peculiarities, Keywords; Fetal MRI, CNS Anomalies, Congenital, Ultrasound. |