الفهرس 
Title : various waves of covid-19 : a comparative study of pattern of liver injury in adult patients in various waves of covid-19 infection
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Abstract
Introduction Patients suffering from novel COVID-19 have varying
liver function abnormalities. Liver injury necessitates a thorough
examination and ongoing monitoring because it can be multifactorial and
heterogeneous. Hepatic involvement in COVID-19 could be related to
underlying liver disease, drugs used to treat COVID-19, a direct effect of
the virus, or a complicated disease course in COVID-19.
Aim of the Work This study aimed at studying liver enzymes
abnormalities through different waves of COVID-19 and finding possible
relations to disease severity.
Methods This retrospective study included 521 patients diagnosed with
COVID-19 infection based on PCR. We retrieved data from medical
records of patients from Kasr Al-Ainy Hospitals, Cairo University,
admitted from April 2020 to October 2021. They were divided according
to the time of admission to the hospital in the four different waves. They
were categorized according to disease severity. We collected medical
data including patient’s demographics (age, gender, comorbidities),
presenting symptoms (general, respiratory, GI), complications in the
course of management, outcome, and relevant laboratory studies (blood
indices, inflammatory markers, and liver enzymes) on the first day of
admission and followed up after five days. Other baseline data included
chest computed tomography (CT) findings were included as well. The
outcome of the study patients was reported