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العنوان
The diagnostic performance of digital breast tomosynthesis in patients with dense breast in relation to MRI /
المؤلف
Elzamly, Alyaa Ahmed Abd Elfattah.
هيئة الاعداد
باحث / علياء أحمد عبد الفتاح الزاملي
مشرف / بسمة عبد المنعم دسوقي
مناقش / محمد شوقي عبد الله
مناقش / شيماء عبد الحميد حسنين
الموضوع
Breast Magnetic resonance imaging. Ultrasonography, Mammary. Tomosynthesis.
تاريخ النشر
2023.
عدد الصفحات
146 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/6/2023
مكان الإجازة
جامعة المنوفية - كلية الطب - قسم الأشعة
الفهرس
Only 14 pages are availabe for public view

from 159

from 159

Abstract

Dense breast tissue represents a major challenge in every day mammographic diagnosis of females with different breast complains and increases the risk of false positive or negative diagnosis.
Breast cancer risk increases with increasing breast density and this provide continuous increasing need for eaely detection and diagnosis of dense breast lesions.
Dynamic contrast enhanced breast magnetic resonance imaging (DCE-MRI) offers the highest sensitivity and specificity of all breast imaging modalities independent of breast density.
DBT is a new imaging modality that has potential for screening women with dense breasts. It has gained increasing interest for routine everyday use with several early clinical studies showing higher accuracy compared to that of DM.
DBT has the ability to reduce breast tissue overlap, thus potentially revealing lesions that would have otherwise been missed.
DBT is easier and less expensive than breast MRI that is also time consuming, feared of by many claustrophobic patients and not suitable for patients with metallic implants.
The present study included 57 female patients with dense breasts to assess the role of DBT relative to breast MRI in diagnosis of different pathologies. We examined all patients by DBT and compared their results to MRI results.
Forty-five patients in our study group had breast masses on DBT and confirmed on MRI. Thirty-eight cases diagnosed as malignant masses and eighteen cases as benign. DBT helped in diagnosis of breast masses with very high sensitivity and specificity.
Summary
130
Non-mass lesions were diagnosed in twelve cases. They were underestimated by DBT that showed significantly lower sensitivity and specificity compared to MRI.
Breast calcification is an important pathological finding seen on DBT. MRI couldn’t diagnose any case of breast calcification which was a superior value of DBT over MRI.
Regarding diagnosis of breast asymmetry and architectural distortion DBT showed significant role with sensitivity and specificity similar to MRI.
We concluded that DBT is an excellent, sensitive and specific imaging technique for screening and diagnosis of dense breast lesions allowing MRI to be reserved for more complicated cases. Its main role was appreciated in diagnosis of breast mass, breast calcifications, asymmetry and architectural distortion. It had limited role in diagnosing patients with non-mass lesions, so MRI showed a great role with those patients.