الفهرس 
CROHN’S DISEASEOnly 14 pages are availabe for public view
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Abstract
Crohn’s disease is one of the inflammatory bowel diseases that may lead to progressive bowel damage and disability.
Therapeutic lines to treat Crohn’s disease (CD) was changed over years, shifting from simply resolving disease symptoms to profound bowel healing, with the aim not only treating short-term complications, but also affecting the natural history of disease by decreasing important outcomes.
Bowel Sonography (BS) is a non-invasive, easy, well tolerated and radiation-free imaging alternative in some situations. BS has a major role in diagnosing and monitoring of many gastro-enteric diseases with increasing IBD management.
Nowadays DWI is routinely used in several clinical scenarios, besides still being a hot research topic: it was tested in almost all cancers to differentiate malignant from benign lesions, to distinguish different malignant histotypes or tumor grades, to predict and/or assess treatment responses, and to identify residual or recurrent tumors in follow-up examinations.
It was a specialized MRI technique to map water diffusion of molecules in biological tissues (Choi et al., 2016). DWI takes less time than other modalities and can be performed without intravenous contrast; a major advantage to avoid the risk of gadolinium-based contrast agents (Thomsen et al., 2013).