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العنوان
The serum-ascites Vitamin D Gradient (SADG): A Diagnostic Marker for Spontaneous Bacterial Peritonitis in Egyptian Cirrhotic Patients /
المؤلف
Elzennary, Maryam Ezzat.
هيئة الاعداد
باحث / مريم عزت الزناري
مشرف / محمد عبدالرازق شرف الدين
مناقش / رضوي محمود الشرابي
مناقش / اسلام احمد هبه
الموضوع
Tropical medicine and infectious diseases.
تاريخ النشر
2023.
عدد الصفحات
116 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكبد
تاريخ الإجازة
19/3/2023
مكان الإجازة
جامعة طنطا - كلية الطب - Tropical medicine and infectious diseases
الفهرس
Only 14 pages are availabe for public view

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from 154

Abstract

Spontaneous bacterial peritonitis (SBP) is the most common infective complication of liver cirrhosis, which is mainly due to Gram-negative bacteria (Pericleous, Sarnowski et al., 2016). Its incidence ranges from 10% to 30%in hospitalized patients, with a mortality as high as 46% (Pericleous, Sarnowski et al., 2016)(Gentile, Buonomo et al., 2017). The cornerstone of the diagnosis of SBP is a polymorph nuclear neutrophil (PMN) count in ascitic fluid exceeding 250 cells/microL. However, it has been suggested that specific molecules in ascitic fluid, namely, C-reactive protein, lactoferrin and calprotectin, may be additional prognostic or diagnostic tools in patients with SBP ( Runyon, 2013 )(Kadam, Acharya et al., 2016).Among its various biological activities, 25- the first catabolite of vitamin D — is involved in the immune response. Low levels of circulating 25-OH vitamin D are associated with infections in patients with cirrhosis (Anty, Tonohouan et al., 2014). Serum 25-OH vitamin D levels are generally lower in these patients than in controls (Putz-Bankuti, Pilz et al., 2012) and even lower in patients with decompensated cirrhosis (Singh, Taneja et al., 2022).