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Abstract
Background: The objective of this study was to evaluate the associations of basal gonadotropins (FSH & LH) with pregnancy rate at IVF/ICSI. Methods: A prospective observational study was conducted at Kasr Al Ainy IVF unit. Patients were 208 women, who underwent IVF/ICSI treatment cycles. Basal FSH and basal LH versus treatment data and pregnancy were measured.Results: Combinations of FSH and LH gave significantly better information than each gonadotropin alone; highest mean pregnancy rate (44%) was achieved in women with low FSH (6.7 U/l) and with high LH levels (4.9 U/l), whereas pregnancy rate was lowest (21.2%) in women with high FSH and low LH levels. Pregnancy rates were intermediate (30{u2013}32%) if FSH and LH were either both low or both high. As for measures of ovarian response and embryo quality followed the same pattern.Conclusions: Low FSH level combined with high LH probably reflects a well- preserved ovarian reserve and is associated with the highest success rates at IVF/ICSI