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Abstract
The aim of this study was to compare between the effects of different exercise intensities on nitric oxide and insulin resistance in type 2 diabetes mellitus. Sixty women patients with type 2 diabetes mellitus selected from Kasr Alaini hospital (out patients diabetes clinic), their age ranged from 40 to 50 years included in the present study. Patients divided into two groups equal in number: group (A) received a program of aerobic exercise practicing on cycle ergometer for 25 minutes three times per week for 8 weeks. group (B) received a protocol of high intensity interval exercise on cycle ergometer for 25 minutes three times per week for 8 weeks. The biochemical changes in nitric oxide and insulin resistance levels were measured at the beginning of the study and after eight weeks. The results showed that nitric oxide increased significantly (P < 0.05) within each group, Significant differences of the post treatment mean values between both groups in favor of group (B) were recorded (p < 0.05), Also it showed that insulin resistance decreased significantly within each group but had no significant difference between both groups. Both traditional moderate intensity exercise and high intensity exercise provided a significant increase in nitric oxide and decrease in insulin resistance. Moderate intensity exercise and high intensity exercise should be considered in the management and rehabilitation of type 2 diabetes mellitus