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Abstract
PET/CT is implemented in the staging of various malignant tumors and more effectively in their follow up , hence, the importance of the evaluation of its efficiency in the detection, characterization and the follow up of skeletal metastases in oncology patient In combined PET/CT, CT images significantly improves PET specificity with better localization of bone metastases and differentiation between benign and malignant lesion. On the other hand, PET can detect bone marrow based metastases early and in the absence of morphologic changes on CT images; thereby improving CT sensitivity. The influence of the integration of PET and CT upon CT specificity is also notable in cases of treated healed metastases which lack metabolic activity in spite of suspicious morphologic appearance