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Abstract
Worldwide, over 265,000 people contract pancreatic cancer annually. According to the national cancer registry program of Egypt (NCRPE) it was estimated that in 2013, (2,262) Egyptians were diagnosed with pancreatic cancer. Seventy five percent of patients die within the first year after diagnosis, making incidence rates almost approaching prevalence. Assess the effectiveness of surgical palliation for pancreatic and periampullary cancers performed at NCI between 2006 and 2010. This is a retrospective study; clinical data, operative data, information regarding the postoperative and follow up period was gathered by reviewing the patients{u2019} hospital records (n = 23) and completed through phone interviews with the patients family members. Gastric bypass procedures were successful in relieving gastric outlet obstruction (GOO) in (83.3%) of cases; they also avoided late GOO in (100.0%) of cases when done prophylactically. Biliary bypass procedures were successful in relieving jaundice in (75.0%) of cases and they proved durability in avoiding recurrent jaundice in (80.0%) of cases. Operative mortality reached (13.6%), while morbidity reached (40.9%). Surgical palliation had no effect on overall survival. Surgical palliation for pancreatic cancer was generally effective and was associated with an operative mortality rate of (13.6%). However morbidity was high, with significant complications occurring in 18.1%