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Abstract
Chronic infection with the hepatitis C virus (HCV) is now the leading cause of liver-related morbidity and mortality; exercise is a low - cost, reliable and sustainable therapy for many chronic diseases. Moderate, long-term physical exercise may increase the production of IL 2, an important regulator of the immune response. HIT can serve as an effective alternate to traditional endurance training, inducing similar or even superior changes in a range of physiological, performance and health - related markers in both healthy individuals and diseased populations. Objective:to investigate the effect of low volume high intensity interval training on IL 2, INFÞ and ALT, AST in HCV patients chronic non cirrhotic active HCV. Subjects and methods:forty patients submitted to low volume high intensity interval training for 2 months 3 sessions per week. Their serum level of IL 2 and INFÞ were measured using ELISA test also serum levels of ALT and AST were measured before and after the interval training. Results showed significant increase in serum levels of IL 2, INFÞ with improvement percentage (48.23%), (21.05%) and decrease in ALT, AST with improvement percentage (18.85%), (23.87%) in the study. Low volume high intensity interval training had a potent effect on immune system in patients with chronic active HCV