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العنوان
Study of prediction of response to pegylated interferon plus ribavirin in hepatitis C patients by IL28B gene variation and its relation to other different predictors /
الناشر
Noran Atef Mahmoud Elkordy ,
المؤلف
Noran Atef Mahmoud Elkordy
تاريخ النشر
2015
عدد الصفحات
184 P. ;
الفهرس
Only 14 pages are availabe for public view

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from 206

Abstract

The current medications for HCV are ribavirin and Pegylated- Interferon. Protease inhibitors are emerging. Accurately predicting the patients who will respond to therapy is becoming important, for patient care and also with respect to the cost. Studies have shown that IL28B are strongly associated with the response to treatment of hepatitis C. We proved in our study on 200 patients that IL28B is the strongest predictor of response of treatment by Peg/ ribavirin and CC allele has the best chance to respond to treatment. Also, BMI, ALT and ALP could be used as predictors for response