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العنوان
New approaches for the uses of active methylene reagents for the synthesis of pharmaceutically active heterocyclic compounds /
الناشر
Noha Mohamed Asaad Bagato ,
المؤلف
Noha Mohamed Asaad Bagato
هيئة الاعداد
باحث / Noha Mohamed Asaad Bagato
مشرف / Rafat Milad Mohareb
مشرف / Rafat Milad Mohareb
مشرف / Rafat Milad Mohareb
تاريخ النشر
2015
عدد الصفحات
131 P. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
11/5/2015
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic chemistry
الفهرس
Only 14 pages are availabe for public view

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from 156

Abstract

In this work the reaction of either 4- methylaniline (1a) or Ü- naphthylamine (1b) with diethyl malonate (2) gave the anilide derivatives 3a and 3b, respectively. The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran and thiazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured