الفهرس 
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Abstract
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a widespread chronic sleep disorder associated with oxyhemoglobin desaturation, sleep disturbance, neurobehavioral symptoms, and cardiovascular sequelae throughout sleep. It is the most common form of sleep related breathing disorders (SRBDs)
The aim of this work was to study the correlation between pulmonary hypertension and serum uric acid level in Obstructive sleep apnea hypopnea syndrome patients with different severities.
This study was conducted on 100 patients referred to sleep unit, Alexandria Main university hospitals in the duration between June 2019 and February 2021.
Patients were divided in to 3 groups. Groups І (mild OSA) included 6 patients (6%), group П (moderate OSA) included 38 patients (38%) and group Ш (severe OSA) included 56 patients (56%).
All patients were subjected to full history taking, Complete physical examination, ESS, many anthropometric measures (height, weight, BMI, neck circumference), serum uric acid sample, echo and full night sleep study.
In our study, 66% of the patients were men and 34% were women with a mean age of 53.04 ± 8.45 years. Patients suffered from comorbidities DM, hypertension. Symptoms were chocking attacks at night, snoring, unrefreshing sleep, witnessed apneas, fatigue, EDS, dry mouth, nocturia and morning headache
Comparing patients with pulmonary hypertension to patients without pulmonary hypertension there was statistically significant difference between both groups regarding age, BMI, AHI, T90% and presence of HTN. But, there was no statistically significant difference between both groups regarding gender, ODI and presence of DM.
Comparing patients with high level of serum uric acid to patients with normal level of serum uric acid there was statistically significant difference between both groups regarding gender, age, BMI, AHI and T90%. But, there was no statistically significant difference between both groups regarding ODI and presence of DM and HTN.
There was a positive correlation between AHI and pulmonary hypertension and level of serum uric acid.