الفهرس 
Non-alcoholic fatty liver disease (NAFLD) severity and associated dietary, exercise and sleep patterns as lifestyle determinants
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Abstract
Background: Nonalcoholic Fatty Liver Disease (NAFLD) has recently become a public health concern as it is among the leading causes of liver cirrhosis and its complications. The development of NAFLD is closely related to lifestyle factors especially dietary intake, physical activity and sleep quality. controlling these lifestyle factors was found to be effective in NAFLD prevention and treatment.
Aim of work:This study aims at assessing the dietary pattern, physical activity and sleep qualityin patients as lifestyle determinants for NAFLD severity.
Subjects and Methods: This was a cross-sectional study conducted onNAFLD patients attending the ultrasound outpatient clinic of Endemic Medicine Department at Cairo University Hospital. A structured interview questionnaireincluding sociodemographic and medical history as well as validated food frequency questionnaire (FFQ), Pittsburg sleep quality index (PSQI) and international physical activity questionnaire (IPAQ)was used to collect patients’ data.
Results:A total number of 77 patients were included in the study. The mean age for patients was 49.74±10.9 years (range 21 to 69).Among patients, 36.4%, 33.8% and 29.9% had liver steatosis grades I(mild), II (moderate) and III (severe) respectively.On univariate analysis,high BMI,high waist circumference, higher daily caloric and carbohydrate intake, poor sleep quality and low physical activity were significantly associatedwith higher steatosis grades.On the multivariate analysis, the independent significant predictors for NAFLD severity were waist circumference (P=0.011, OR 1.119), Poor sleep quality (P=0.038, OR 3.871) and physical activity (P=0.027, OR 4.6).
Conclusion:Waist circumference, poor sleep quality and low physical activity grade were the actual significant predictors for NAFLD severity