الفهرس 
Acute coronary syndromeOnly 14 pages are availabe for public view
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Abstract
of this study was to evaluate the association of serum uric acid
level with angiographic severity of coronary artery disease in patients with
ACS.
This observational study was conducted in cardiology department of
Menoufia University Hospital and included 60 patients who were admitted by
ACS in the period from August 2021 and September 2021. Serum uric acid
was measured at time of admission. Coronary angiography was performed
using the Judkins technique and severity of coronary artery disease was
calculated by Gensini score.
The mean age of the whole population was 56.52 ± 11.68 years with
male percentage 58.3%. Sixty-four (76.6%) had STEMI while 14 (23.4%) had
UA/NSTEMI. Among the studied group, serum uric acid level ranged from
3.50 to 11.0 mg/dl, with a mean 7.18 ± 2.33 mg/dl. According to serum uric
acid levels, patients were divided to two categories; 31 (51.7%) patients were
normouricemic and 29 (48.3 %) patients were hyperuricemic. Mean Gensini
score value was 37.16 ± 14.93 in the normouricemic and 79.17 ± 26.56 in
hyperuricemic group. There was a significant relation between serum uric
acid level and the value of Gensini score (p<0.001). The mean level of serum
uric acid was higher in patients with Gensini score of ≥40 in comparison with
those with values 1-39 (8.32 ± 1.92 mg/dl versus 5.05 ± 1.29 mg/dl, p
Summary
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<0.001). Using Pearson correlation coefficient to assess the correlation
between serum uric acid and Gensini score, it shows that there is a statistically
significant positive correlation (r=0.838, p<0.001).
We concluded that there was a positive correlation between serum uric
acid level with the severity of coronary artery disease in patients presented by
ACS.