الفهرس 
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Abstract
C
ontrolled (deliberate/induced) hypotension is a technique by which the arterial blood pressure is lowered in a controllable manner to reduce surgical blood loss and improve the operative field visibility.
In this study, we aimed to evaluate the efficacy of dexmedetomidine (DEX) as a hypotensive agent in comparison to nitroglycerin (NTG) in FESS regarding the reduction of mean arterial blood pressure, HR, decrease inhalational anesthetic requirements (MAC), surgical field quality, increase the time to first postoperative analgesic request, increase hemodynamics stability and decrease postoperative complications.
In the present study we noted that, during the operation the mean values of heart rate were lower among dexmedetomidine group than nitroglycerine group while the mean arterial blood pressure values were comparable between both groups, and after stopping the infusion the mean values of heart rate and blood pressure were lower among dexmedetomidine group than nitroglycerine group.
Maximum isoflurane concentration was higher among nitroglycerine group, the surgical field quality was assessed with the use of ACS when we achieve the target MAP 60-70mmHg the ACS 2-3 was achieved, the time to recovery was longer among dexmedetomidine group.
During the postoperative periods the mean values of heart rate and blood pressure were lower among dexmedetomidine group than nitroglycerine group, time needed to reach modified Aldert score above 9 was longer among dexmedetomidine group, time to reach the first postoperative analgesic request was longer among dexmedetomidine group than nitroglycerin group, and postoperative complications incidence was lower among dexmedetomidine group than nitroglycerine group.