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Abstract Advances in endovascular therapies during the past decade have broadened the options for treating peripheral vascular disease percutaneously. Endovascular treatment offers a lower risk alternative to open surgery in many patients with multiple comorbidities. Noninvasive physiological tests and arterial imaging precede an endovascular intervention and help localize the disease and plan the procedure.The present study was a one year clinical prospective interventional study aimed to studying the use of calcification scoring systems to investigate the association between arterial peripheral calcification and one-year primary patency after endovascular intervention, and also to studying the association between arterial peripheral calcification and major adverse limb event [MALE] rate at 12 months of follow up in patients with a de novo lower limb arterial lesion who were admitted to Vascular Surgery Department, Assiut University Hospital, Assiut, Egypt for endovascular intervention in the period from the 1st of October 2020 up to the end of October 2021.The study included 93 patients (according to the used calcification scoring systems; 40 patients had mild calcification and 53 patients had severe calcification) The mean age of the studied participants was 59.31 ± 6.46 years (range 50 -75) years Male predominance among studied patients with peripheral arterial calcificationVascular calcification is intimately entwined with the presence of chronic diseases (i.e., ischemic heart disease, chronic kidney disease) Ischemic heart disease and CKD was found to be a significant risk factor for development of MALE The primary patency rate shows no significant difference according to the presence of calcification The presence of calcification increases the incidence of vascular restenosis over timeAccurate assessment of calcification level and patterns by calcification scoring systems is useful in maximizing the efficacy of endovascular therapy. |