الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Coronary artery disease is considered one of the most common diseases. Developing countries contributed to 80 percent of CVD deaths. Diabetes mellitus is a chronic disease that occurs when the body cannot produce enough or effectively use of insulin and are induced by a genetic predisposition coupled with environmental factors. As type 2 diabetes shares several risk factors in common with coronary artery disease (CAD), such as age, hypertension, dyslipidemia, obesity, physical inactivity and stress, an increase in the prevalence of diabetes indirectly implicates an escalating risk of CAD as well. Gensini score is one of the most widely used scoring systems in cardiology. It is an objective method to determine the severity of CAD according to angiographic findings. The objective of the current study was to evaluate the association between Gensini score and the duration of diabetes in patients undergoing coronary angiography. This study was carried out in Coronary Angiography Cath Lab in Cardiology Department, Faculty of Medicine, Tanta University Hospital. This study included 300 clinically diagnosed cases of diabetes on proper anti-diabetic treatment, with referral for diagnostic coronary angiography. All patients were subjected to full history taking, physical examination, laboratory investigations (including lipid profile, complete blood count and readings of fasting and post prandial blood sugar) and angiographic examination. In the present study, there were 197 males and 103 females (65.7% and 34.3% respectively), ranging in age from 31 to 87 years old with a mean of 57.01 ± 9.944 years. The mean BMI was 27.77 ± 2.042kg/m2, ranging from 23 to 34 kg/m2. Regarding smoking in the present study, 143 (47.7%) of our study participants were smokers. The current study demonstrated that 183 (61.0%) of the patients were hypertensives. The mean duration of DM of the current studied sample was 13.97 ± 7.570 years (range from 2 to 35 years). In the current study, the mean Gensini score was 36.96 ± 33.303, (range from 0 to 143). Age, smoking, duration of DM, cholesterol, TG, and ECG were statistically significantly positively correlated with Gensini score, while female gender showed statistically significant negative correlation with it. Also, the mean Gensini Score was statistically significantly higher in patients with ischemic changes than in patients without ischemic changes. Therefore, the duration of DM was statistically significant predictor of Gensini score.