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العنوان
Phytochemical and biological investigation of mastic oleoresin /
المؤلف
Rashwan, Ayatallah Magdy Farid Zaki Mohamed .
هيئة الاعداد
باحث / ايه الله مجدي فريد
مشرف / محمد ابراهيم ابو شعير
مشرف / هدي فتحي الشريف
مشرف / انجي ابراهيم احمد
الموضوع
Pharmacognosy
تاريخ النشر
2023.
عدد الصفحات
62 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - عقاقير
الفهرس
Only 14 pages are availabe for public view

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from 62

Abstract

Natural products often provide new main compounds that can be used for drug discovery. Because of the complexity of natural product discovery, pharmaceutical companies have paid little attention to it in the past couple of decades. A recent article that was published in 2022 offered a description of different modern approaches utilized in drug discovery from all-natural sources, underscoring that the most crucial first step in the process of drug discovery is the selection of plants targeted for screening, which involves 3 approaches as follows, selection-based on Ethnopharmacological understanding (based on the empirical experience), random approaches, as well as technique based on conventional medical system. Then, the second step is the authentication of the collected materials, which is regarded as the fundamental starting point in the development of natural products including taxonomic, chemometric, spectroscopic, microscopic, macroscopic, immunoassays as well as DNA fingerprinting evaluation. Eventually, the final step is the extraction and separation of natural compounds utilizing biological activity-guided fractionation. (Pirintsos et al., 2022)