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العنوان
Development and evaluation of brain-targeted nano-delivery systems for management of multiple sclerosis/
المؤلف
Abdelarahman, Lamiaa Ramadan Abdelalim .
هيئة الاعداد
باحث / لمياء رمضان عبدالعليم عبدالرحمن
مشرف / أسامة يوسف عبد الله
مشرف / فاطمة اسماعيل
مشرف / يسرا شعبان ربيع النجار
الموضوع
Pharmaceutics.
تاريخ النشر
2023.
عدد الصفحات
169 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - صيدلانيات
الفهرس
Only 14 pages are availabe for public view

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Abstract

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease affecting the central nervous system, where immune cells attack self-myelin sheath. Myelin sheath is a protective insulating layer surrounding nerve axons. The myelin sheath function is mainly to protect neurons and accelerate signal transduction, therefore myelin damage would result in slower and lower signal transfer followed by nerve axons damage and loss of functions (1). Symptoms of MS varies according to the site of injured nerves including; optic neuritis, tremors, lack of coordination, numbness or weakness of limbs, slurred speech, fatigue, sub-acute motor function loss and pain.