الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
SARS-COV-2 Virus 1. Background
The national Institute of fitness of China in 2019 informed the world health organization (WHO) to several cases of pneumonia in Wuhan, China. Patients have been reported to have ingested Huanan seafood, despite the fact that other early cases had no touch with such seafood.(1) Early on January 2020, a brand new coronavirus, at first defined by WHO as 2019-nCoV, with a diagnostic modality of throat swab sample.(2) This pathogen renamed into Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Several cases have been infected with Coronavirus,(3) and the virus was named by WHO as Coronavirus disease 2019 (Covid-19). At the middle of January 2020, around seven thousand cases and twelve thousand suspected cases were reported in China, and 80 confirmed instances had been observed in about twenty different international locations.(4) WHO declared that SARS-CoV-2 is an epidemic condition and a public outbreak.(4)
In line with the national fitness commission of China, at the beginning of February 2020, the case fatality rate amongst infected cases in China was 2%(5) and outside of China was 0.2%.(6) The case fatality rate for patients admitted to hospitals with confirmed covid-19 infection was ranged between 10% to 15%.(7, 8) COVID-19 is considered to be a very infectious disease with a high mortality rate.
2. Covid-19 Virus Classification and Origin
SARS-CoV-2 belongs to the Coronaviridae family, which consists of two subfamilies, Coronavirinae and Torovirinae. Furthermore, members of the subfamily Coronavirinae are divided into four genera:
1) Alphacoronavirus that involves human coronavirus (HCoV)-229E and HCoV-NL63.
2) Betacoronavirus which contains HCoV-OC43, human severe acute respiratory syndrome coronavirus (SARS-HCoV), and Middle East respiratory syndrome coronavirus (MERS-CoV).
3) Gamma Coronavirus including whale and bird viruses.
4) Deltacoronavirus isolated from pigs and birds.(9)
SARS-CoV-2 is considered a betacoronavir together with other two very infectious viruses; SARS-CoV and MERS-CoV.
SARS-CoV-2 is, by definition, an enveloped, positive, single-stranded RNA virus (+ssRNA).(10) SARS-CoV-2 is a beta-coronavirus that affects human beings.(11) Analysis of SARS-CoV-2 genome showed that the virus is closely related (90%) to other SARS-like bat coronaviruses discovered in China in early 2019, and is different in its genetic form from SARS-CoV.(11)
Using the molecular base of SARS-CoV-2,(12) another study reported that the virus is in close similarity to BatCoV, which is a bat coronavirus was reported in the past in Yunnan Province, with 90% similarity in its structure.(12) Previous study noted that there is no clear evidence of similarity with other bat viruses such as BatCoV, and SARSr-CoV to the SARS-CoV-2.(12) However, different studies claimed that covid-19 virus host might be bats.(11, 12)
Moreover, it is still no clear whether any intermediate host contribute to the humans transmission of the virus. Bats were considered to be highly unlikely to be the direct host for transmitting the virus to humans for several reasons