الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Worldwide, CAD is the leading cause of death. The prevalence of hypertension has been increasing and remains the leading cause of CVD and death worldwide. Lowering BP reduces the risk of CVD and death, but the optimal BP target has been extensively debated.
Although numerous studies observed an inverse relationship between DBP and adverse cardiac ischemic events (i.e., the lower the diastolic pressure the greater the risk of coronary heart disease and adverse outcomes), other studies found no evidence for a relationship between DBP and adverse CVD outcomes; including MI, and denied the existence of a J-curve.
Therefore, the relationship between DBP level and detailed characterization and quantification of the atherosclerotic burden has not been clarified.
Accordingly, this study purposed to assess the relationship between DBP and the severity as well as the burden of coronary artery atherosclerotic lesions quantified by syntax score and syntax score II scores.
This study included 300 patients with obstructive coronary artery disease as detected by coronary angiography, SYNTAX score and SYNTAX score II were calculated and blood pressure was measured in all patients. Patients were divided into three groups according to SYNTAX score and SYNTAX score II scores; Regarding SYNTAX score: 210 patients (70%) had low SYNTAX score (0-22), 62 patients (20.6%) had intermediate score (23-32) and 28 patients (9.33%) had high SYNTAX score (≥33). Regarding SYNTAX score II:136 patients (45.3%) had low SYNTAX score II (≤21), 78 patients (26%) had intermediate score (>21– ≤28) and 86 patients (28.6%) had high SYNTAX score II (>28).
In this study, patients were predominantly males (72%). Their age ranged from 35 to 82 years mean age of 59.55 ± 9.44 years.
Hypertension was the most frequent risk factor (71%), followed by diabetes (47%), smoking (37.3%), and dyslipidemia (24.7%). No statistically significant difference between low, intermediate, and high SYNTAX score groups as regards these risk factors.
Regarding drug history, 170 (56.7%) patients were on BB, 112 (37.3%) were on CCB, 162 (54%) were on ACE