الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Colorectal cancer (CRC) is one of the health care challenges and the second leading cause of cancer-related death worldwide. It is influenced by environmental aspects, and the intestinal microbiota is an important contributor. Using LC MS/MS technique, stool samples of five females were analyzed. A total of 360 proteins were highly expressed. Proteomic analysis was carried out using UniprotKB database to survey the microbial community associated with CRC. Proteins from the four phyla Actinobacteria, Bacteroidetes, Firmicutes and Proteobacteria constituted 75 % of the microbial proteins within the human GIT. Gene ontology of proteins revealed that most of these proteins are involved in different bacterial functions.Among the highly expressed proteins were transketolase, sushi domain-containing protein, carbonic anhydrase, arylsulfatase, alkaline phosphatase, phosphoglycerate kinase, Acyl-CoA synthetase, enolase and EF-hand domain-containing protein. These proteins could be used as potential tumor markers for CRC.