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العنوان
Computer modeling of calcium and potassium channels dendritic distributions in spinal motoneurons /
الناشر
Mohamed Hisham Abdelgawad Mousa ,
المؤلف
Mohamed Hisham Abdelgawad Mousa
تاريخ النشر
2017
عدد الصفحات
70 P. :
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study integrates the recent experimental findings and explains the functional roles of small conductance potassium (SK) channels and the L-type calcium channels besides investigating their punctate pattern distributions over the motoneuron dendritic tree. it includes the modeling of the warm-up property for the L-type calcium channels and revised SK channels kinetic models to match the calcium ion concentrations sensitivity of the experimental behaviors. The results show that the punctate pattern distributions provide a functional advantage for enhancing the synaptic currents in Ü-motoneurons