الفهرس 
Title : Correlation between preoperative endoscopic findings and computed tomography with postoperative histopathology in the staging of cancer larynx
AbstractOnly 14 pages are availabe for public view
 |  | from | 103 |  |  |
| | | from | 103 | | |
Abstract
Objective to assess the accuracy of preoperative CT and clinical/endoscopic staging of laryngeal tumors by comparing clinical and imaging findings of each modality with histologic cross-sections of surgical specimens and impact of these diagnostic modalities on pretherapeutic staging of laryngeal carcinoma. Methods a prospective study where Thirty patients with cancer larynx underwent surgical treatment (Total or partial laryngectomy) at ORL department of Kasr Alainy medical college, Cairo university during the period of June 2015 to November 2016. All patients underwent transnasal fiberoptic laryngoscopy with photographic documentation. CT Axial slices of 2-mm thickness with contrast was obtained. The surgical specimens were cut in whole-organ slices parallel to the plane of the axial CT (2 mm thickness). Results Histopathological examination of the surgical specimens revealed 3 patients with T1, 5 with T2, 13 with T3 and 9 with T4. When compared with pathologic stage, endoscopic classification was correct in 14 cases. CT scan was correct in 20 of cases. The T stage was correctly determined by both endoscope and CT scan in 23 cases. The agreement between perceived T stage by endoscope and CT with histopathological analysis was 100% for T1, 66.7% for T2, 80% for T3 and 66.6% for T4. Conclusion The role of Multi Slice CT scan (MSCT) in the preoperative TNM classification of laryngeal carcinoma has been well documented. MSCT is superior to laryngoscopy in the evaluation of T3 and T4 tumors. On the contrary, laryngoscopy is better than MSCT in the evaluation of T1 and T2 lesions. Information gained by MSCT and laryngoscopy significantly improves preoperative staging accuracy of laryngeal carcinoma