الفهرس Only 14 pages are availabe for public view
 |  | from | 129 |  |  |
| | | from | 129 | | |
Abstract
Background : Acute Kidney Injury is common in critically ill children admitted to pediatric intensive care unit.. Recently, a group of pediatric and adult nephrologists and intensivists founded the Acute Dialysis Quality Initiative and proposed a consensus definition called the RIFLE classification. (Bellomo et al., 2004). This definition is based on serum creatinine and urine output, and it was derived to reflect the dynamic process of ARF, which can progress from mild to severe form. The development of a noninvasive biomarker that could diagnose renal dysfunction early in sepsis or other circumstances and that could also monitor the response to therapy .Patients and Methods:We have included all patients admitted to pediatric intensive care unit of King Abdulaziz university hospital, for 1 year.We excluded neonates and children with a history of, or evidence of, chronic kidney disease (CKD). Our study was conducted through 2 steps: In the 1st step we have reviewed the charts, clinical history, examinations and laboratory and radiological investigations of 281 children admitted to (PICU). We identified any patient with acute kidney injury according modified pediatric RIFLE Criteria at the time of admission or during treatment at the pediatric Intensive care unit. The 2nd step: We followed 62 patients prospectively who admitted to PICU in last 3 month of same year with .Serum creatinine and serum cystatin C both were taken on admission (0 time), 6 hours and 12 hours, after admission