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Abstract The thesis involves the synthesis and characterization of [Pd(ETEA)Cl₂] complex; where ETEA = 2-(ethylthio)ethylamine. TEM and DLS were carried out for morphology and particle size and distribution investigation. Stoichiometry and stability constants of the complexes formed between various biologically relevant ligands (amino acids, peptides, DNA constituents and dicarboxylic acids) and [Pd(ETEA)(H₂O)₂]2+ are investigated at 25{u00BA}C and at constant 0.1 M ionic strength. The concentration distributions diagrams of the various species formed are evaluated. Thermogravimetric analysis for Pd(ETEA)Cl₂ is studied. The TGA curves of Pd(ETEA)Cl₂ exhibits four decomposition steps, respectively, leaving a residue of palladium metal. The thermodynamic parameters of the decomposition steps for Pd(ETEA)Cl₂ were calculated using coats-redfern and horowitz-metzger methods. X-ray single crystals of [Pd(ETEA)Cl₂] is studied. Density functional theory (DFT) calculations have been carried out to investigate the most stable geometries of the ligands, Pd(ETEA)Cl₂ complex. Biological activities of Pd(ETEA)Cl₂) against microbes and tumor cells were carried out |