الفهرس 
Evaluation of thoracic aortic calcification as a predictor of development of atherosclerotic coronary artery disease using multi-slice computed tomography coronary angiography
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Abstract
The presence and extent of coronary artery calcium (CAC) is an independent predictor of atherosclerotic coronary artery disease (CAD) morbidity and mortality. Few studies have evaluated interactions or independent incremental risk for coronary and thoracic aortic calcification (TAC). The independent predictive value of TAC for atherosclerotic CAD is not well-established. Evaluation of TAC as a predictor of development of atherosclerotic CAD using MSCT coronary angiography. Two hundred sixty four patients were subjected to non-contrast CT examination to calculate TAC and CAC agatston method followed by MSCT coronary angiography. The mean age of the study population was 54.3±11years (47.7% females). 52.7% of the study population had agatston TAC scores of 0; 6.8% of 1 to 9 (minimal calcification); 17.4% of 10 to 99(mild calcification); 14.4% of 100 to 399 (moderate calcification) and 8.7% of 400 (significant calcification). TAC was seen in 47.3% of the study population, with females showing a slightly higher prevalence than males (27% vs.21%). In our study, 34% had no detectable CAC and TAC, 16% had TAC>0 in presence of no CAC, 19% had CAC>0 but no detectable TAC and 31% had presence of both CAC and TAC. There is significant difference of age, gender, hypertension and DM among different TAC categories. Atherosclerotic CAD was identified by CT coronary angiography in 65.91% of the studied population, only 26.14% of studied population had obstructive CAD (lesion {u2265}50% of the vessel lumen). By comparing log TAC score between different groups of atherosclerotic CAD (absent, non-obstructive and obstructive CAD), we found a significant difference (p value 0.014) among these groups